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Effect of RAS status on anti-EGFR monoclonal antibodies + 5-FU infusion-based chemotherapy in first-line treatment of metastatic colorectal cancer: A meta-analysis

PURPOSE: To investigate the effect of RAS on anti-EGFR moAb + 5-FU infusion based chemotherapy in first-line treatment of mCRC. METHODS: The MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane databases and ClinicalTrials.gov databases were independently reviewed. Primary end p...

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Detalles Bibliográficos
Autores principales: Zhou, Mingyi, Yu, Ping, Hou, Kezuo, Fu, Lingyu, Chen, Ying, Qu, Jinglei, Qu, Xiujuan, Liu, Yunpeng, Zhang, Jingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908286/
https://www.ncbi.nlm.nih.gov/pubmed/27331015
http://dx.doi.org/10.1016/j.mgene.2016.05.001