Cargando…

Effect of RAS status on anti-EGFR monoclonal antibodies + 5-FU infusion-based chemotherapy in first-line treatment of metastatic colorectal cancer: A meta-analysis

PURPOSE: To investigate the effect of RAS on anti-EGFR moAb + 5-FU infusion based chemotherapy in first-line treatment of mCRC. METHODS: The MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane databases and ClinicalTrials.gov databases were independently reviewed. Primary end p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Mingyi, Yu, Ping, Hou, Kezuo, Fu, Lingyu, Chen, Ying, Qu, Jinglei, Qu, Xiujuan, Liu, Yunpeng, Zhang, Jingdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908286/ https://www.ncbi.nlm.nih.gov/pubmed/27331015 http://dx.doi.org/10.1016/j.mgene.2016.05.001

Ejemplares similares

β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis
por: Liu, Jing, et al.
Publicado: (2011)

A Prognostic Model in Metastatic or Recurrent Gastric Cancer Patients with Good Performance Status Who Received First-Line Chemotherapy()
por: Wang, Jin, et al.
Publicado: (2016)

Phase III Trials of Standard Chemotherapy with or without Bevacizumab for Ovarian Cancer: A Meta-Analysis
por: Zhou, Mingyi, et al.
Publicado: (2013)

A novel function of hepatocyte growth factor in the activation of checkpoint kinase 1 phosphorylation in colon cancer cells
por: Song, Na, et al.
Publicado: (2017)

5-FU-Induced Upregulation of Exosomal PD-L1 Causes Immunosuppression in Advanced Gastric Cancer Patients
por: Zhang, Min, et al.
Publicado: (2020)

Ubiquitin Ligase Cbl-b Is Involved in Icotinib (BPI-2009H)-Induced Apoptosis and G1 Phase Arrest of EGFR Mutation-Positive Non-Small-Cell Lung Cancer
por: Mu, Xiaodong, et al.
Publicado: (2013)

Nomogram-based prediction of survival in unresectable or metastatic gastric cancer patients with good performance status who received first-line chemotherapy
por: Wang, Jin, et al.
Publicado: (2020)

The dynamic monitoring of CEA in response to chemotherapy and prognosis of mCRC patients
por: Yu, Ping, et al.
Publicado: (2018)

Clinical significance of pAkt and pErk1/2 expression in early-stage breast cancer patients treated with anthracycline-based adjuvant chemotherapy
por: LIU, WENJUAN, et al.
Publicado: (2015)

Cbl-b Enhances Sensitivity to 5-Fluorouracil via EGFR- and Mitochondria-Mediated Pathways in Gastric Cancer Cells
por: Feng, Dan, et al.
Publicado: (2013)

CXCL12/SDF-1α induces migration via SRC-mediated CXCR4-EGFR cross-talk in gastric cancer cells
por: Cheng, Yu, et al.
Publicado: (2017)

Who will benefit more from maintenance therapy of metastatic colorectal cancer?
por: Zhou, Mingyi, et al.
Publicado: (2017)

RANKL/RANK promotes the migration of gastric cancer cells by interacting with EGFR
por: Wan, Xing, et al.
Publicado: (2020)

Phase I dose-escalation trial of irinotecan with continuous infusion 5-FU first line, in metastatic colorectal cancer
por: Saunders, M P, et al.
Publicado: (2004)

DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53-deficient pancreatic cancer cells
por: Jing, Wei, et al.
Publicado: (2018)

Assessment of Nine Driver Gene Mutations in Surgically Resected Samples from Patients with Non-Small-Cell Lung Cancer
por: Wang, Shuo, et al.
Publicado: (2020)

MicroRNA-29b-2-5p inhibits cell proliferation by directly targeting Cbl-b in pancreatic ductal adenocarcinoma
por: Li, Ce, et al.
Publicado: (2018)

Caveolin-1 enhances RANKL-induced gastric cancer cell migration
por: Wang, Yan, et al.
Publicado: (2018)

Systematic Review on Infusion Reactions Associated with Chemotherapies and Monoclonal Antibodies for Metastatic Colorectal Cancer
por: Song, Xue, et al.
Publicado: (2011)

Expression of pEGFR and pAKT as response-predictive biomarkers for RAS wild-type patients to anti-EGFR monoclonal antibodies in metastatic colorectal cancers
por: Harlé, A, et al.
Publicado: (2015)

Impact of primary tumor location in patients with RAS wild-type metastatic colon cancer treated with first-line chemotherapy plus anti-EGFR or anti-VEGF monoclonal antibodies: a retrospective multicenter study
por: Grassadonia, Antonino, et al.
Publicado: (2019)

Case Report: Fluzoparib for multiple lines of chemotherapy refractory in metastatic cutaneous squamous cell carcinoma with BRCA2 pathogenic mutation
por: Sun, Xin, et al.
Publicado: (2022)

Complete Pathologic Response of Multiple Liver Metastases and Clinical Complete Response of Rectal Cancer in a Patient with Ataxia-Telangiectasia Mutated Gene Mutations After XELOXIRI Plus Bevacizumab: A Case Report
por: Cheng, Yu, et al.
Publicado: (2021)

Interferon-α Enhances 5′-Deoxy-5-Fluorouridine-Induced Apoptosis by ERK-Dependant Upregulation of Thymidine Phosphorylase
por: Zhu, Yike, et al.
Publicado: (2013)

Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells
por: Gong, Jing, et al.
Publicado: (2020)

Comparative Analysis and in vitro Experiments of Signatures and Prognostic Value of Immune Checkpoint Genes in Colorectal Cancer
por: Ma, Rui, et al.
Publicado: (2021)

Retracted: Upregulation of Serine Proteinase Inhibitor Clade B Member 3 (SERPINB3) Expression by Stromal Cell-Derived Factor (SDF-1)/CXCR4/Nuclear Factor kappa B (NF-κB) Promotes Migration and Invasion of Gastric Cancer Cells
por: Gong, Jing, et al.
Publicado: (2023)

LncRNA APCDD1L-AS1 induces icotinib resistance by inhibition of EGFR autophagic degradation via the miR-1322/miR-1972/miR-324-3p-SIRT5 axis in lung adenocarcinoma
por: Wu, Jie, et al.
Publicado: (2021)

Dynamics of RAS/BRAF Mutations in cfDNA from Metastatic Colorectal Carcinoma Patients Treated with Polychemotherapy and Anti-EGFR Monoclonal Antibodies
por: Rachiglio, Anna Maria, et al.
Publicado: (2022)

Correction to: LncRNA APCDD1L-AS1 induces icotinib resistance by inhibition of EGFR autophagic degradation via the miR-1322/miR-1972/ miR-324-3p-SIRT5 axis in lung adenocarcinoma
por: Wu, Jie, et al.
Publicado: (2021)

Correction: LncRNA APCDD1L-AS1 induces icotinib resistance by inhibition of EGFR autophagic degradation via the miR-1322/miR-1972/ miR-324-3p-SIRT5 axis in lung adenocarcinoma
por: Wu, Jie, et al.
Publicado: (2023)

M2 macrophage infiltration into tumor islets leads to poor prognosis in non-small-cell lung cancer
por: Cao, Lili, et al.
Publicado: (2019)

NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
por: Yan, Hongfei, et al.
Publicado: (2019)

Localization of GPSM2 in the Nucleus of Invasive Breast Cancer Cells Indicates a Poor Prognosis
por: Deng, Mingming, et al.
Publicado: (2020)

Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex
por: Fang, Wanxia, et al.
Publicado: (2020)

Correction to: Sur-X, a novel peptide, kills colorectal cancer cells by targeting survivin-XIAP complex
por: Fang, Wanxia, et al.
Publicado: (2021)

microRNA-569 inhibits tumor metastasis in pancreatic cancer by directly targeting NUSAP1
por: Guo, Xiaohui, et al.
Publicado: (2022)

Evolution of RAS Mutational Status in Liquid Biopsies During First-Line Chemotherapy for Metastatic Colorectal Cancer
por: Klein-Scory, Susanne, et al.
Publicado: (2020)

Prognostic and predictive biomarkers for anti-EGFR monoclonal antibody therapy in RAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis
por: Lu, Xiaona, et al.
Publicado: (2023)

No effect of dose, hepatic function, or nutritional status on 5-FU clearance following continuous (5-day), 5-FU infusion.
por: Fleming, R. A., et al.
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_sibv27j4kvf617gv2ikrv842tg