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Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes

Motivation: For many classes of disease the same genetic risk variants underly many related phenotypes or disease subtypes. Multinomial logistic regression provides an attractive framework to analyze multi-category phenotypes, and explore the genetic relationships between these phenotype categories....

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Detalles Bibliográficos
Autores principales: Jostins, Luke, McVean, Gilean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908321/
https://www.ncbi.nlm.nih.gov/pubmed/26873930
http://dx.doi.org/10.1093/bioinformatics/btw075