Prediction of ribosome footprint profile shapes from transcript sequences

Motivation: Ribosome profiling is a useful technique for studying translational dynamics and quantifying protein synthesis. Applications of this technique have shown that ribosomes are not uniformly distributed along mRNA transcripts. Understanding how each transcript-specific distribution arises is...

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Detalles Bibliográficos
Autores principales: Liu, Tzu-Yu, Song, Yun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908337/
https://www.ncbi.nlm.nih.gov/pubmed/27307616
http://dx.doi.org/10.1093/bioinformatics/btw253