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Reconstructing the temporal progression of HIV-1 immune response pathways

Motivation: Most methods for reconstructing response networks from high throughput data generate static models which cannot distinguish between early and late response stages. Results: We present TimePath, a new method that integrates time series and static datasets to reconstruct dynamic models of...

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Detalles Bibliográficos
Autores principales: Jain, Siddhartha, Arrais, Joel, Venkatachari, Narasimhan J., Ayyavoo, Velpandi, Bar-Joseph, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908338/
https://www.ncbi.nlm.nih.gov/pubmed/27307624
http://dx.doi.org/10.1093/bioinformatics/btw254