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A novel method for discovering local spatial clusters of genomic regions with functional relationships from DNA contact maps
Motivation: The three-dimensional structure of genomes makes it possible for genomic regions not adjacent in the primary sequence to be spatially proximal. These DNA contacts have been found to be related to various molecular activities. Previous methods for analyzing DNA contact maps obtained from...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908340/ https://www.ncbi.nlm.nih.gov/pubmed/27307607 http://dx.doi.org/10.1093/bioinformatics/btw256 |