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RCK: accurate and efficient inference of sequence- and structure-based protein–RNA binding models from RNAcompete data

Motivation: Protein–RNA interactions, which play vital roles in many processes, are mediated through both RNA sequence and structure. CLIP-based methods, which measure protein–RNA binding in vivo, suffer from experimental noise and systematic biases, whereas in vitro experiments capture a clearer si...

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Detalles Bibliográficos
Autores principales: Orenstein, Yaron, Wang, Yuhao, Berger, Bonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908343/
https://www.ncbi.nlm.nih.gov/pubmed/27307637
http://dx.doi.org/10.1093/bioinformatics/btw259