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An integer programming framework for inferring disease complexes from network data
Motivation: Unraveling the molecular mechanisms that underlie disease calls for methods that go beyond the identification of single causal genes to inferring larger protein assemblies that take part in the disease process. Results: Here, we develop an exact, integer-programming-based method for asso...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908347/ https://www.ncbi.nlm.nih.gov/pubmed/27307626 http://dx.doi.org/10.1093/bioinformatics/btw263 |