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An integer programming framework for inferring disease complexes from network data

Motivation: Unraveling the molecular mechanisms that underlie disease calls for methods that go beyond the identification of single causal genes to inferring larger protein assemblies that take part in the disease process. Results: Here, we develop an exact, integer-programming-based method for asso...

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Detalles Bibliográficos
Autores principales: Mazza, Arnon, Klockmeier, Konrad, Wanker, Erich, Sharan, Roded
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908347/
https://www.ncbi.nlm.nih.gov/pubmed/27307626
http://dx.doi.org/10.1093/bioinformatics/btw263