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Structure-based prediction of transcription factor binding specificity using an integrative energy function

Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regulation networks. In this article, we present a struct...

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Detalles Bibliográficos
Autores principales: Farrel, Alvin, Murphy, Jonathan, Guo, Jun-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908348/
https://www.ncbi.nlm.nih.gov/pubmed/27307632
http://dx.doi.org/10.1093/bioinformatics/btw264