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Linear effects models of signaling pathways from combinatorial perturbation data
Motivation: Perturbations constitute the central means to study signaling pathways. Interrupting components of the pathway and analyzing observed effects of those interruptions can give insight into unknown connections within the signaling pathway itself, as well as the link from the pathway to the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908352/ https://www.ncbi.nlm.nih.gov/pubmed/27307630 http://dx.doi.org/10.1093/bioinformatics/btw268 |