Using genomic annotations increases statistical power to detect eGenes

Motivation: Expression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method to determine whether a gene is an eGene req...

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Detalles Bibliográficos
Autores principales: Duong, Dat, Zou, Jennifer, Hormozdiari, Farhad, Sul, Jae Hoon, Ernst, Jason, Han, Buhm, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Ismb 2016 Proceedings July 8 to July 12, 2016, Orlando, Florida
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908356/
https://www.ncbi.nlm.nih.gov/pubmed/27307612
http://dx.doi.org/10.1093/bioinformatics/btw272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908356/
https://www.ncbi.nlm.nih.gov/pubmed/27307612
http://dx.doi.org/10.1093/bioinformatics/btw272

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