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Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways

Gnat(−/−), Cnga3(−/−), Opn4(−/−) triple knockout (TKO) mice lack essential components of phototransduction signalling pathways present in rods, cones and photosensitive retinal ganglion cells (pRGCs), and are therefore expected to lack all sensitivity to light. However, a number of studies have show...

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Detalles Bibliográficos
Autores principales: Hughes, Steven, Rodgers, Jessica, Hickey, Doron, Foster, Russell G., Peirson, Stuart N., Hankins, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908426/
https://www.ncbi.nlm.nih.gov/pubmed/27301998
http://dx.doi.org/10.1038/srep28086