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Characterisation of light responses in the retina of mice lacking principle components of rod, cone and melanopsin phototransduction signalling pathways
Gnat(−/−), Cnga3(−/−), Opn4(−/−) triple knockout (TKO) mice lack essential components of phototransduction signalling pathways present in rods, cones and photosensitive retinal ganglion cells (pRGCs), and are therefore expected to lack all sensitivity to light. However, a number of studies have show...
Autores principales: | Hughes, Steven, Rodgers, Jessica, Hickey, Doron, Foster, Russell G., Peirson, Stuart N., Hankins, Mark W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908426/ https://www.ncbi.nlm.nih.gov/pubmed/27301998 http://dx.doi.org/10.1038/srep28086 |
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