Topological constraints of structural elements in regulation of catalytic activity in HDV-like self-cleaving ribozymes

Self-cleaving ribozymes fold into intricate structures, which orient active site groups into catalytically competent conformations. Most ribozyme families have distinct catalytic cores stabilized by tertiary interactions between domains peripheral to those cores. We show that large hepatitis delta v...

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Detalles Bibliográficos
Autores principales: Webb, Chiu-Ho T., Nguyen, Dang, Myszka, Marie, Lupták, Andrej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908430/
https://www.ncbi.nlm.nih.gov/pubmed/27302490
http://dx.doi.org/10.1038/srep28179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908430/
https://www.ncbi.nlm.nih.gov/pubmed/27302490
http://dx.doi.org/10.1038/srep28179

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