Cargando…
Topological constraints of structural elements in regulation of catalytic activity in HDV-like self-cleaving ribozymes
Self-cleaving ribozymes fold into intricate structures, which orient active site groups into catalytically competent conformations. Most ribozyme families have distinct catalytic cores stabilized by tertiary interactions between domains peripheral to those cores. We show that large hepatitis delta v...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908430/ https://www.ncbi.nlm.nih.gov/pubmed/27302490 http://dx.doi.org/10.1038/srep28179 |