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Multiple ion channel block by the cation channel inhibitor SKF‐96365 in myocytes from the rabbit atrioventricular node

The atrioventricular node (AVN) of the cardiac conduction system coordinates atrial–ventricular excitation and can act as a subsidiary pacemaker. Recent evidence suggests that an inward background sodium current, I (B,Na), carried by nonselective cation channels (NSCCs), contributes to AVN cell pace...

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Detalles Bibliográficos
Autores principales: Cheng, Hongwei, Curtis, Alexander E., Fellingham, Claire, Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908495/
https://www.ncbi.nlm.nih.gov/pubmed/27288059
http://dx.doi.org/10.14814/phy2.12819