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Two orthorhombic polymorphs of hydromorphone
Conditions to obtain two polymorphic forms by crystallization from solution were determined for the analgesic drug hydromorphone [C(17)H(19)NO(3); systematic name: (4R,4aR,7aR,12bS)-9-hydroxy-3-methyl-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one]. These two crystal...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908523/ https://www.ncbi.nlm.nih.gov/pubmed/27308029 http://dx.doi.org/10.1107/S2056989016006563 |