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Significance of 1B and 2B domains in modulating elastic properties of lamin A

Nuclear lamins are type V intermediate filament proteins which form an elastic meshwork underlying the inner nuclear membrane. Lamins directly contribute to maintain the nuclear shape and elasticity. More than 400 mutations have been reported in lamin A that are involved in diseases known as laminop...

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Detalles Bibliográficos
Autores principales: Bera, Manindra, Ainavarapu, Sri Rama Koti, Sengupta, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908593/
https://www.ncbi.nlm.nih.gov/pubmed/27301336
http://dx.doi.org/10.1038/srep27879