Autophagy induction targeting mTORC1 enhances Mycobacterium tuberculosis replication in HIV co-infected human macrophages

To survive and replicate in macrophages Mycobacterium tuberculosis (Mtb) has developed strategies to subvert host defence mechanisms, including autophagy. Autophagy induction has the potential to clear Mtb, but little is known about its effect during controlled tuberculosis and HIV co-infection. Mam...

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Detalles Bibliográficos
Autores principales: Andersson, Anna-Maria, Andersson, Blanka, Lorell, Christoffer, Raffetseder, Johanna, Larsson, Marie, Blomgran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908603/
https://www.ncbi.nlm.nih.gov/pubmed/27302320
http://dx.doi.org/10.1038/srep28171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908603/
https://www.ncbi.nlm.nih.gov/pubmed/27302320
http://dx.doi.org/10.1038/srep28171

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