IGF-1 protects tubular epithelial cells during injury via activation of ERK/MAPK signaling pathway

Injury of renal tubular epithelial cells can induce acute renal failure and obstructive nephropathy. Previous studies have shown that administration of insulin-like growth factor-1 (IGF-1) ameliorates the renal injury in a mouse unilateral ureteral obstruction (UUO) model, whereas the underlying mec...

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Detalles Bibliográficos
Autores principales: Wu, Zengbin, Yu, Yang, Niu, Lei, Fei, Aihua, Pan, Shuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908659/
https://www.ncbi.nlm.nih.gov/pubmed/27301852
http://dx.doi.org/10.1038/srep28066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908659/
https://www.ncbi.nlm.nih.gov/pubmed/27301852
http://dx.doi.org/10.1038/srep28066

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