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HDAC inhibitors, MS-275 and salermide, potentiates the anticancer effect of EF24 in human pancreatic cancer cells

Histone deacetylases (HDACs) play a major role in the regulation of chromatin structure and gene expression by changing acetylation status of histone and non-histone proteins. MS-275 (entinostat, MS) is a well-known benzamide-based HDACI and Salermide (SAL), a reverse amide compound HDACI, have anti...

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Detalles Bibliográficos
Autores principales: Yar Saglam, Atiye Seda, Yilmaz, Akin, Onen, Hacer Ilke, Alp, Ebru, Kayhan, Handan, Ekmekci, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908665/
https://www.ncbi.nlm.nih.gov/pubmed/27330528
http://dx.doi.org/10.17179/excli2016-186