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Prenatal exposure to the organophosphate insecticide chlorpyrifos enhances brain oxidative stress and prostaglandin E(2) synthesis in a mouse model of idiopathic autism

BACKGROUND: Autism spectrum disorders (ASD) are emerging as polygenic and multifactorial disorders in which complex interactions between defective genes and early exposure to environmental stressors impact on the correct neurodevelopment and brain processes. Organophosphate insecticides, among which...

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Detalles Bibliográficos
Autores principales: De Felice, Alessia, Greco, Anita, Calamandrei, Gemma, Minghetti, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908699/
https://www.ncbi.nlm.nih.gov/pubmed/27301868
http://dx.doi.org/10.1186/s12974-016-0617-4