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Prenatal exposure to the organophosphate insecticide chlorpyrifos enhances brain oxidative stress and prostaglandin E(2) synthesis in a mouse model of idiopathic autism
BACKGROUND: Autism spectrum disorders (ASD) are emerging as polygenic and multifactorial disorders in which complex interactions between defective genes and early exposure to environmental stressors impact on the correct neurodevelopment and brain processes. Organophosphate insecticides, among which...
Autores principales: | De Felice, Alessia, Greco, Anita, Calamandrei, Gemma, Minghetti, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908699/ https://www.ncbi.nlm.nih.gov/pubmed/27301868 http://dx.doi.org/10.1186/s12974-016-0617-4 |
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