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Methotrexate efficacy, but not its intolerance, is associated with the dose and route of administration

BACKGROUND: There is a lack of published evidence on the importance of methotrexate (MTX) dose and route of administration on both its efficacy and adverse events in children with Juvenile Idiopathic Arthritis (JIA). We aimed to document our clinical practice based on the treat-to-target approach in...

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Detalles Bibliográficos
Autores principales: Fráňová, J., Fingerhutová, Š., Kobrová, K., Srp, R., Němcová, D., Hoza, J., Uher, M., Saifridová, M., Linková, L., Doležalová, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908704/
https://www.ncbi.nlm.nih.gov/pubmed/27301536
http://dx.doi.org/10.1186/s12969-016-0099-z