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High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)
BACKGROUND: Polymorphic loci exist throughout the genomes of a population and provide the raw genetic material needed for a species to adapt to changes in the environment. The minor allele frequencies of rare Single Nucleotide Polymorphisms (SNPs) within a population have been difficult to track wit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908710/ https://www.ncbi.nlm.nih.gov/pubmed/27301885 http://dx.doi.org/10.1186/s12864-016-2669-3 |