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High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)

BACKGROUND: Polymorphic loci exist throughout the genomes of a population and provide the raw genetic material needed for a species to adapt to changes in the environment. The minor allele frequencies of rare Single Nucleotide Polymorphisms (SNPs) within a population have been difficult to track wit...

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Detalles Bibliográficos
Autores principales: Preston, Jessica L., Royall, Ariel E., Randel, Melissa A., Sikkink, Kristin L., Phillips, Patrick C., Johnson, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908710/
https://www.ncbi.nlm.nih.gov/pubmed/27301885
http://dx.doi.org/10.1186/s12864-016-2669-3