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Oncolytic herpes simplex virus kills stem-like tumor-initiating colon cancer cells

Stem-like tumor-initiating cells (TICs) are implicated in cancer progression and recurrence, and can be identified by sphere-formation and tumorigenicity assays. Oncolytic viruses infect, replicate in, and kill a variety of cancer cells. In this study, we seek proof of principle that TICs are suscep...

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Detalles Bibliográficos
Autores principales: Warner, Susanne G, Haddad, Dana, Au, Joyce, Carson, Joshua S, O’Leary, Michael P, Lewis, Christina, Monette, Sebastien, Fong, Yuman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909096/
https://www.ncbi.nlm.nih.gov/pubmed/27347556
http://dx.doi.org/10.1038/mto.2016.13