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Oncolytic herpes simplex virus kills stem-like tumor-initiating colon cancer cells
Stem-like tumor-initiating cells (TICs) are implicated in cancer progression and recurrence, and can be identified by sphere-formation and tumorigenicity assays. Oncolytic viruses infect, replicate in, and kill a variety of cancer cells. In this study, we seek proof of principle that TICs are suscep...
Autores principales: | Warner, Susanne G, Haddad, Dana, Au, Joyce, Carson, Joshua S, O’Leary, Michael P, Lewis, Christina, Monette, Sebastien, Fong, Yuman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909096/ https://www.ncbi.nlm.nih.gov/pubmed/27347556 http://dx.doi.org/10.1038/mto.2016.13 |
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