Characterization of Staphylococcus aureus Primosomal DnaD Protein: Highly Conserved C-Terminal Region Is Crucial for ssDNA and PriA Helicase Binding but Not for DnaA Protein-Binding and Self-Tetramerization

The role of DnaD in the recruitment of replicative helicase has been identified. However, knowledge of the DNA, PriA, and DnaA binding mechanism of this protein for the DnaA- and PriA-directed replication primosome assemblies is limited. We characterized the DNA-binding properties of DnaD from Staph...

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Detalles Bibliográficos
Autores principales: Huang, Yen-Hua, Lien, Yi, Huang, Chien-Chih, Huang, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909229/
https://www.ncbi.nlm.nih.gov/pubmed/27304067
http://dx.doi.org/10.1371/journal.pone.0157593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909229/
https://www.ncbi.nlm.nih.gov/pubmed/27304067
http://dx.doi.org/10.1371/journal.pone.0157593

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