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Bacillus anthracis Spore Surface Protein BclA Mediates Complement Factor H Binding to Spores and Promotes Spore Persistence

Spores of Bacillus anthracis, the causative agent of anthrax, are known to persist in the host lungs for prolonged periods of time, however the underlying mechanism is poorly understood. In this study, we demonstrated that BclA, a major surface protein of B. anthracis spores, mediated direct binding...

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Detalles Bibliográficos
Autores principales: Wang, Yanyu, Jenkins, Sarah A., Gu, Chunfang, Shree, Ankita, Martinez-Moczygemba, Margarita, Herold, Jennifer, Botto, Marina, Wetsel, Rick A., Xu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909234/
https://www.ncbi.nlm.nih.gov/pubmed/27304426
http://dx.doi.org/10.1371/journal.ppat.1005678