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Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus

Peripheral muscarinic acetylcholine receptors regulate insulin and glucagon release in rodents but their importance for similar roles in humans is unclear. Bethanechol, an acetylcholine analogue that does not cross the blood-brain barrier, was used to examine the role of peripheral muscarinic signal...

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Detalles Bibliográficos
Autores principales: Chowdhury, Sara, Wang, Songyan, Dunai, Judit, Kilpatrick, Rachel, Oestricker, Lauren Z., Wallendorf, Michael J., Patterson, Bruce W., Reeds, Dominic N., Wice, Burton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909255/
https://www.ncbi.nlm.nih.gov/pubmed/27304975
http://dx.doi.org/10.1371/journal.pone.0156852