Cargando…

Genetic Drift, Purifying Selection and Vector Genotype Shape Dengue Virus Intra-host Genetic Diversity in Mosquitoes

Due to their error-prone replication, RNA viruses typically exist as a diverse population of closely related genomes, which is considered critical for their fitness and adaptive potential. Intra-host demographic fluctuations that stochastically reduce the effective size of viral populations are a ch...

Descripción completa

Detalles Bibliográficos
Autores principales: Lequime, Sebastian, Fontaine, Albin, Ar Gouilh, Meriadeg, Moltini-Conclois, Isabelle, Lambrechts, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909269/
https://www.ncbi.nlm.nih.gov/pubmed/27304978
http://dx.doi.org/10.1371/journal.pgen.1006111