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Genetic Drift, Purifying Selection and Vector Genotype Shape Dengue Virus Intra-host Genetic Diversity in Mosquitoes

Due to their error-prone replication, RNA viruses typically exist as a diverse population of closely related genomes, which is considered critical for their fitness and adaptive potential. Intra-host demographic fluctuations that stochastically reduce the effective size of viral populations are a ch...

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Detalles Bibliográficos
Autores principales:	Lequime, Sebastian, Fontaine, Albin, Ar Gouilh, Meriadeg, Moltini-Conclois, Isabelle, Lambrechts, Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909269/ https://www.ncbi.nlm.nih.gov/pubmed/27304978 http://dx.doi.org/10.1371/journal.pgen.1006111

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