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Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases
Segmented negative strand RNA viruses of the arena-, bunya- and orthomyxovirus families uniquely carry out viral mRNA transcription by the cap-snatching mechanism. This involves cleavage of host mRNAs close to their capped 5′ end by an endonuclease (EN) domain located in the N-terminal region of the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909276/ https://www.ncbi.nlm.nih.gov/pubmed/27304209 http://dx.doi.org/10.1371/journal.ppat.1005636 |