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Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation

To identify new proteins required for faithful meiotic chromosome segregation, we screened a Schizosaccharomyces pombe deletion mutant library and found that deletion of the dbl2 gene led to missegregation of chromosomes during meiosis. Analyses of both live and fixed cells showed that dbl2Δ mutant...

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Detalles Bibliográficos
Autores principales: Polakova, Silvia, Molnarova, Lucia, Hyppa, Randy W., Benko, Zsigmond, Misova, Ivana, Schleiffer, Alexander, Smith, Gerald R., Gregan, Juraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909299/
https://www.ncbi.nlm.nih.gov/pubmed/27304859
http://dx.doi.org/10.1371/journal.pgen.1006102