Cargando…

Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation

To identify new proteins required for faithful meiotic chromosome segregation, we screened a Schizosaccharomyces pombe deletion mutant library and found that deletion of the dbl2 gene led to missegregation of chromosomes during meiosis. Analyses of both live and fixed cells showed that dbl2Δ mutant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Polakova, Silvia, Molnarova, Lucia, Hyppa, Randy W., Benko, Zsigmond, Misova, Ivana, Schleiffer, Alexander, Smith, Gerald R., Gregan, Juraj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909299/ https://www.ncbi.nlm.nih.gov/pubmed/27304859 http://dx.doi.org/10.1371/journal.pgen.1006102

Ejemplares similares

A knockout screen for protein kinases required for the proper meiotic segregation of chromosomes in the fission yeast Schizosaccharomyces pombe
por: Kovacikova, Ines, et al.
Publicado: (2013)

DNA intermediates of meiotic recombination in synchronous S. pombe at optimal temperature
por: Hyppa, Randy W., et al.
Publicado: (2014)

Mal3, the Schizosaccharomyces pombe homolog of EB1, is required for karyogamy and for promoting oscillatory nuclear movement during meiosis
por: Polakova, Silvia, et al.
Publicado: (2014)

Chromosome Segregation: Monopolin Attracts Condensin
por: Dudas, Andrej, et al.
Publicado: (2011)

Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation
por: Phadnis, Naina, et al.
Publicado: (2015)

Indistinguishable Landscapes of Meiotic DNA Breaks in rad50(+) and rad50S Strains of Fission Yeast Revealed by a Novel rad50(+) Recombination Intermediate
por: Hyppa, Randy W., et al.
Publicado: (2008)

Repression of a large number of genes requires interplay between homologous recombination and HIRA
por: Misova, Ivana, et al.
Publicado: (2021)

Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe
por: Sanyal, Swastika, et al.
Publicado: (2018)

ATP analog-sensitive Pat1 protein kinase for synchronous fission yeast meiosis at physiological temperature
por: Cipak, Lubos, et al.
Publicado: (2012)

RAD54 is essential for RAD51-mediated repair of meiotic DSB in Arabidopsis
por: Hernandez Sanchez-Rebato, Miguel, et al.
Publicado: (2021)

Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination
por: Su, Hang, et al.
Publicado: (2017)

SCF Ensures Meiotic Chromosome Segregation Through a Resolution of Meiotic Recombination Intermediates
por: Okamoto, Shin-ya, et al.
Publicado: (2012)

A failure of meiotic chromosome segregation in a fbh1Δ mutant correlates with persistent Rad51-DNA associations
por: Sun, Weili, et al.
Publicado: (2011)

RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51
por: Kovalenko, Oleg V., et al.
Publicado: (2006)

PLP inhibits the activity of interphase centrosomes to ensure their proper segregation in stem cells
por: Lerit, Dorothy A., et al.
Publicado: (2013)

ETAA1 ensures proper chromosome segregation: A matter of S phase or mitosis?
por: González Besteiro, Marina Alejandra, et al.
Publicado: (2019)

Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity
por: Lim, Kim Kiat, et al.
Publicado: (2021)

Cystathionine β‐synthase is required for oocyte quality by ensuring proper meiotic spindle assembly
por: Cao, Yan, et al.
Publicado: (2022)

Chromosome Segregation: Disarming the Protector
por: Sanyal, Swastika, et al.
Publicado: (2013)

Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation
por: Kuga, T, et al.
Publicado: (2014)

RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella
por: Charlot, Florence, et al.
Publicado: (2014)

A Key Tumor Suppressor Protein Ensures Proper Chromosome Segregation during Cell Division
por: Hoff, Mary
Publicado: (2006)

FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination
por: Ito, Masaru, et al.
Publicado: (2023)

Meiotic Recombination in Arabidopsis Is Catalysed by DMC1, with RAD51 Playing a Supporting Role
por: Da Ines, Olivier, et al.
Publicado: (2013)

The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes
por: Kim, Kyeoung-Hwa, et al.
Publicado: (2016)

RAD51AP2 is required for efficient meiotic recombination between X and Y chromosomes
por: Ma, Hui, et al.
Publicado: (2022)

Roles of XRCC2, RAD51B and RAD51D in RAD51-Independent SSA Recombination
por: Serra, Heïdi, et al.
Publicado: (2013)

Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation
por: Izawa, Daisuke, et al.
Publicado: (2012)

Kinetochores attached to microtubule-ends are stabilised by Astrin bound PP1 to ensure proper chromosome segregation
por: Conti, Duccio, et al.
Publicado: (2019)

New evidence that SAC can tolerate misaligned chromosomes in mouse oocytes
por: Polakova, Silvia, et al.
Publicado: (2012)

Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor
por: Greenhough, Luke A., et al.
Publicado: (2023)

Differing Requirements for RAD51 and DMC1 in Meiotic Pairing of Centromeres and Chromosome Arms in Arabidopsis thaliana
por: Da Ines, Olivier, et al.
Publicado: (2012)

ATM Promotes RAD51-Mediated Meiotic DSB Repair by Inter-Sister-Chromatid Recombination in Arabidopsis
por: Yao, Yuan, et al.
Publicado: (2020)

Proteomic analysis of meiosis and characterization of novel short open reading frames in the fission yeast Schizosaccharomyces pombe
por: Huraiova, Barbora, et al.
Publicado: (2020)

Homologous Pairing Activities of Two Rice RAD51 Proteins, RAD51A1 and RAD51A2
por: Morozumi, Yuichi, et al.
Publicado: (2013)

Meiotic functions of RAD18
por: Inagaki, Akiko, et al.
Publicado: (2011)

Rad51 and Dmc1 Form Mixed Complexes Associated with Mouse Meiotic Chromosome Cores and Synaptonemal Complexes
por: Tarsounas, Madalena, et al.
Publicado: (1999)

Rad51 paralogs Rad55-Rad57 balance the anti-recombinase Srs2 in Rad51 filament formation
por: Liu, Jie, et al.
Publicado: (2011)

Ensuring fidelity of chromosome segregation
por: Ünal, Elçin, et al.
Publicado: (2018)

Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction
por: Subramanyam, Shyamal, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_kogs28vbeovdd2526tattfqses