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4-Phenylbutyric Acid Induces Protection against Pulmonary Arterial Hypertension in Rats

BACKGROUND: Endoplasmic reticulum (ER) stress has been implicated in the pathophysiology of various pulmonary diseases via the activation of the unfolded protein response. However, the role of ER stress in pulmonary arterial hypertension (PAH) remains unclear. The well-known chemical chaperone 4-phe...

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Detalles Bibliográficos
Autores principales: Wu, Yun, Adi, Dilare, Long, Mei, Wang, Jie, Liu, Fen, Gai, Min-Tao, Aierken, Alidan, Li, Ming-Yuan, Li, Qian, Wu, Lei-Qi, Ma, Yi-Tong, Hujiaaihemaiti, Minawaer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909300/
https://www.ncbi.nlm.nih.gov/pubmed/27304885
http://dx.doi.org/10.1371/journal.pone.0157538