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Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

B-cells not only produce immunoglobulins and present antigens to T-cells, but also additional key roles in the immune system. Current knowledge on the role of B-cells in infections caused by intracellular bacteria is fragmentary and contradictory. We therefore analysed the phenotypical and functiona...

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Detalles Bibliográficos
Autores principales: Joosten, Simone A., van Meijgaarden, Krista E., del Nonno, Franca, Baiocchini, Andrea, Petrone, Linda, Vanini, Valentina, Smits, Hermelijn H., Palmieri, Fabrizio, Goletti, Delia, Ottenhoff, Tom H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909319/
https://www.ncbi.nlm.nih.gov/pubmed/27304615
http://dx.doi.org/10.1371/journal.ppat.1005687