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BMP2, a key to uncover luminal breast cancer origin linked to pollutant effects on epithelial stem cells niche
Chronic exposure of epithelial cells to high levels of bone morphogenetic protein 2 (BMP2) has recently been demonstrated to initiate stem cell transformation toward a luminal tumor-like phenotype through a BMP2–BMPR1B-dependent mechanism. Carcinogen-driven deregulation of the stem cell niche could...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909443/ https://www.ncbi.nlm.nih.gov/pubmed/27314065 http://dx.doi.org/10.1080/23723556.2015.1026527 |