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USP11: A key regulator of cIAP2 stability and sensitivity to SMAC mimetics

The critical function of cellular inhibitor of apoptosis proteins (cIAPs) in the protection of cancer cells from numerous apoptotic stimuli prompted the development of second mitochondria-derived activator of caspases (SMAC) mimetics. We recently addressed a novel survival pathway in which cIAP2 is...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Woo, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909448/
https://www.ncbi.nlm.nih.gov/pubmed/27314066
http://dx.doi.org/10.1080/23723556.2015.1029829