Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors()()

Enhanced autophagy has been observed in hypoxic regions of solid tumors. Here we address the hypothesis that autophagy is required for survival of hypoxic cells. We evaluated sensitivity to hypoxia of three human tumor cell lines (MCF7, PC3, and LNCaP) and their autophagy-deficient variants with shR...

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Detalles Bibliográficos
Autores principales: Tan, Qian, Wang, Marina, Yu, Man, Zhang, Junyan, Bristow, Robert G, Hill, Richard P, Tannock, Ian F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909700/
https://www.ncbi.nlm.nih.gov/pubmed/27292024
http://dx.doi.org/10.1016/j.neo.2016.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909700/
https://www.ncbi.nlm.nih.gov/pubmed/27292024
http://dx.doi.org/10.1016/j.neo.2016.04.003

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