Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype

Myelodysplastic syndromes (MDS) are characterized by bone marrow cytological dysplasia and ineffective hematopoiesis in the setting of recurrent somatic gene mutations and chromosomal abnormalities. The underlying pathogenic mechanisms that drive a common clinical phenotype from a diverse array of g...

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Detalles Bibliográficos
Autores principales: Sallman, David A., Cluzeau, Thomas, Basiorka, Ashley A., List, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909736/
https://www.ncbi.nlm.nih.gov/pubmed/27379212
http://dx.doi.org/10.3389/fonc.2016.00151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909736/
https://www.ncbi.nlm.nih.gov/pubmed/27379212
http://dx.doi.org/10.3389/fonc.2016.00151

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