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No major effects of vitamin D(3) (1,25 dihydroxyvitamin D(3)) on absorption and pharmacokinetics of folic acid and fexofenadine in healthy volunteers
PURPOSE: In Caco-2 cells, folate uptake via the proton-coupled folate transporter (PCFT) increases significantly by a 3-day treatment with 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). Additionally, mRNA content and protein expression of the transporter OATP1A2 were increased up to ninefold with 1,2...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909797/ https://www.ncbi.nlm.nih.gov/pubmed/27023466 http://dx.doi.org/10.1007/s00228-016-2050-0 |