No major effects of vitamin D(3) (1,25 dihydroxyvitamin D(3)) on absorption and pharmacokinetics of folic acid and fexofenadine in healthy volunteers

PURPOSE: In Caco-2 cells, folate uptake via the proton-coupled folate transporter (PCFT) increases significantly by a 3-day treatment with 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)). Additionally, mRNA content and protein expression of the transporter OATP1A2 were increased up to ninefold with 1,2...

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Detalles Bibliográficos
Autores principales: Kullak-Ublick, Gerd A., Gubler, Christoph, Spanaus, Katharina, Ismair, Manfred G., Claro da Silva, Tatiana, Jetter, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909797/
https://www.ncbi.nlm.nih.gov/pubmed/27023466
http://dx.doi.org/10.1007/s00228-016-2050-0

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