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Restricting calcium currents is required for correct fiber type specification in skeletal muscle

Skeletal muscle excitation-contraction (EC) coupling is independent of calcium influx. In fact, alternative splicing of the voltage-gated calcium channel Ca(V)1.1 actively suppresses calcium currents in mature muscle. Whether this is necessary for normal development and function of muscle is not kno...

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Detalles Bibliográficos
Autores principales: Sultana, Nasreen, Dienes, Beatrix, Benedetti, Ariane, Tuluc, Petronel, Szentesi, Peter, Sztretye, Monika, Rainer, Johannes, Hess, Michael W., Schwarzer, Christoph, Obermair, Gerald J., Csernoch, Laszlo, Flucher, Bernhard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909858/
https://www.ncbi.nlm.nih.gov/pubmed/26965373
http://dx.doi.org/10.1242/dev.129676