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Restricting calcium currents is required for correct fiber type specification in skeletal muscle
Skeletal muscle excitation-contraction (EC) coupling is independent of calcium influx. In fact, alternative splicing of the voltage-gated calcium channel Ca(V)1.1 actively suppresses calcium currents in mature muscle. Whether this is necessary for normal development and function of muscle is not kno...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909858/ https://www.ncbi.nlm.nih.gov/pubmed/26965373 http://dx.doi.org/10.1242/dev.129676 |