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Centrosomal protein CP110 controls maturation of the mother centriole during cilia biogenesis

Defects in cilia centrosomal genes cause pleiotropic clinical phenotypes, collectively called ciliopathies. Cilia biogenesis is initiated by the interaction of positive and negative regulators. Centriolar coiled coil protein 110 (CP110) caps the distal end of the mother centriole and is known to act...

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Detalles Bibliográficos
Autores principales: Yadav, Sharda Prasad, Sharma, Neel Kamal, Liu, Chunqiao, Dong, Lijin, Li, Tiansen, Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909859/
https://www.ncbi.nlm.nih.gov/pubmed/26965371
http://dx.doi.org/10.1242/dev.130120