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Serum Gelatinases Levels in Multiple Sclerosis Patients during 21 Months of Natalizumab Therapy
Background. Natalizumab is a highly effective treatment approved for multiple sclerosis (MS). The opening of the blood-brain barrier mediated by matrix metalloproteinases (MMPs) is considered a crucial step in MS pathogenesis. Our goal was to verify the utility of serum levels of active MMP-2 and MM...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909921/ https://www.ncbi.nlm.nih.gov/pubmed/27340316 http://dx.doi.org/10.1155/2016/8434209 |