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Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

A total of 15 SNPs within complement genes and present on the ImmunoChip were analyzed in The Environmental Determinants of Diabetes in the Young (TEDDY) study. A total of 5474 subjects were followed from three months of age until islet autoimmunity (IA: n = 413) and the subsequent onset of type 1 d...

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Detalles Bibliográficos
Autores principales: Törn, Carina, Liu, Xiang, Hagopian, William, Lernmark, Åke, Simell, Olli, Rewers, Marian, Ziegler, Anette-G, Schatz, Desmond, Akolkar, Beena, Onengut-Gumuscu, Suna, Chen, Wei-Min, Toppari, Jorma, Mykkänen, Juha, Ilonen, Jorma, Rich, Stephen S., She, Jin-Xiong, Sharma, Ashok, Steck, Andrea, Krischer, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910045/
https://www.ncbi.nlm.nih.gov/pubmed/27306948
http://dx.doi.org/10.1038/srep27887