Phosphoinositide 3-Kinase (PI3K) Subunit p110δ Is Essential for Trophoblast Cell Differentiation and Placental Development in Mouse

Maternal PI3K p110δ has been implicated in smaller litter sizes in mice, but its underlying mechanism remains unclear. The placenta is an indispensable chimeric organ that supports mammalian embryonic development. Using a mouse model of genetic inactivation of PI3K p110δ (p110δ(D910A/D910A)), we sho...

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Detalles Bibliográficos
Autores principales: Hu, Xiwen, Li, Jiangchao, Zhang, Qianqian, Zheng, Lingyun, Wang, Guang, Zhang, Xiaohan, Zhang, Jingli, Gu, Quliang, Ye, Yuxiang, Guo, Sun-Wei, Yang, Xuesong, Wang, Lijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910077/
https://www.ncbi.nlm.nih.gov/pubmed/27306493
http://dx.doi.org/10.1038/srep28201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910077/
https://www.ncbi.nlm.nih.gov/pubmed/27306493
http://dx.doi.org/10.1038/srep28201

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