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Targeted therapeutics in SLE: emerging strategies to modulate the interferon pathway

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by impaired immune tolerance, resulting in the generation of pathogenic autoantibodies and immune complexes. Although autoreactive B lymphocytes have been the first targets for biologic therapies in SLE, the importan...

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Detalles Bibliográficos
Autores principales: Oon, Shereen, Wilson, Nicholas J, Wicks, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910120/
https://www.ncbi.nlm.nih.gov/pubmed/27350879
http://dx.doi.org/10.1038/cti.2016.26