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Association of mutations in V3/C3 domain with enhanced sensitivity of HIV-1 clade C primary envelopes to autologous broadly neutralizing plasma antibodies

BACKGROUND: Broadly neutralizing antibodies to HIV-1 elicited in infected individuals evolves through shifts in their molecular specificities to viral envelope (Env) in the disease course. Recently, we showed that resistance of circulating HIV-1 clade C to the autologous plasma obtained from one Ind...

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Detalles Bibliográficos
Autores principales: Deshpande, Suprit, Patil, Shilpa, Kumar, Rajesh, Shrivastava, Tripti, Srikrishnan, Aylur K., Murugavel, Kailapuri G., Koff, Wayne C., Chakrabarti, Bimal K., Bhattacharya, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910206/
https://www.ncbi.nlm.nih.gov/pubmed/27307004
http://dx.doi.org/10.1186/s12977-016-0273-x